REST Rabbit anti-Human, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-560-984	Proteintech Group Inc 222421AP150UL	150 μL

Description

Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.

Specifications

• Antigen: REST
• Applications: Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Rat
• Gene Accession No.: O54963, Q13127
• Gene ID (Entrez): 5978, 83618
• Immunogen: REST Fusion Protein Ag17707
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: REST

• Concentration: 0.4 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: NRSF, REST, X2 box repressor, XBR
• Gene Symbols: REST
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody