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Phospho-Ku70 (Ser5) Polyclonal Antibody, Invitrogen™

Catalog No. PIPA538257
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100 μg
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Catalog No. Quantity
PIPA538257 100 μg
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Catalog No. PIPA538257 Supplier Thermo Scientific Supplier No. PA538257

Description

Rabbit Polyclonal Antibody

The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-Ku70 (Ser5)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene XRCC6
Gene Accession No. P12956, P23475
Gene Alias CTC75, CTCBF, G22P1, KU70, ML8, TLAA, 5′-dRP lyase Ku70, 5′-deoxyribose-5-phosphate lyase Ku70, 70 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, ATP-dependent DNA helicase II, 70 kDa subunit, CTC box binding factor 75 kDa subunit, CT
Gene Symbols XRCC6
Host Species Rabbit
Immunogen A synthetic phosphopeptide derived from human Ku70 around the phosphorylation site of Ser5 (W-E-SP-Y-Y)
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14375, 2547
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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