Invitrogen™ MD-1 Monoclonal Antibody (MD113)

Rat Monoclonal Antibody

Supplier:  Invitrogen™ MA140039

Catalog No. 01-676-495

Description

MA1-40039 detects MD-1 from mouse samples. MA1-40039 has been successfully used in flow cytometry and functional assay applications. The MA1-40039 immunogen is mouse MD-1 extracellular protein. Endotoxin level < 24 EU/mg.

MD-1, also known as LY86, is a glycoprotein involved in innate immunity. It is a component of the RP105/MD-1 complex, which is expressed primarily in immune cells like B-cells. MD-1 is structurally similar to MD-2, sharing only 16% sequence identity, yet both are implicated in lipopolysaccharide recognition. The protein contains the ML (MD-2-related lipid-recognition) domain, which is conserved across various species and mediates diverse biological functions by interacting with specific lipids. Structurally, MD-1 is characterized by a beta-rich fold consisting of multiple strands, which is integral to its biological activities. Though MD-1 mainly associates with RP105, its role in lipid recognition suggests functional similarities with proteins such as GM2A and NPC2, implying participation in broader immune signaling pathways.

Specifications

• Antigen: MD-1
• Classification: Monoclonal
• Concentration: 0.1 mg/mL
• Formulation: PBS with 0.1% BSA and no preservative
• Gene Accession No.: O88188
• Gene Symbols: LY86
• Immunogen: Murine MD-1 extracellular protein.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Flow Cytometry, Functional Assay
• Clone: MD113
• Conjugate: Unconjugated
• Gene: LY86
• Gene Alias: dJ80N2.1; Ly86; Ly-86; Lymphocyte antigen 86; MD1; MD-1; MD-1, RP105-associated; MMD-1; Protein MD-1; RP1-80N2.1
• Host Species: Rat
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 17084
• Content And Storage: 4°C
• Form: Liquid

Safety and Handling

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