Invitrogen™ GRASP1 Polyclonal Antibody

Catalog No.	Quantity
PIPA532105	100 μL

Catalog No. PIPA532105

Supplier: Invitrogen™ PA532105

Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, HeLa, HepG2. Predicted reactivity: Mouse (94%), Rat (93%), Bovine (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo (Scannevin and Huganir, 2000). Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity (Ye et al., 2000).

Specifications

• Antigen: GRASP1
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
• Gene: GRIPAP1
• Gene Accession No.: Q4V328
• Gene Alias: 30kDa C-terminus form; AI854681; DXImx47e; Grasp1; GRASP-1; GRASP-1 C-terminal chain; GRIP1; GRIP-1; GRIP1 associated protein 1; GRIP1-associated protein 1; Gripap1; GRIP-associated protein 1; HCMV-interacting protein; Kiaa1167; mKIAA1167; MPMGp800B12492Q3; Sfc10
• Gene Symbols: GRIPAP1
• Host Species: Rabbit
• Immunogen: Recombinant protein encompassing a sequence within the center region of human GRASP1. The exact sequence is proprietary.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 56850
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG