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Invitrogen™ Dynein Monoclonal Antibody (74.1)
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Catalog No. MA1070
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100 μg
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MA1070 100 μg
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Catalog No. MA1070 Supplier Invitrogen™ Supplier No. MA1070
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Description

Mouse Monoclonal Antibody

MA1-070 detects two isoforms of the ~74 kDa polypetide of cytoplasmic dynein. MA1-070 has been successfully used in Western blot immunofluorescence, and immunoprecipitation procedures. In Western blot analysis of HeLa cell lysate this antibody detects a ~74 kDa protein representing cytoplasmic dynein. The MA1-070 immunogen is purified bovine brain cytoplasmic dynein.

The directed movement of membrane-bounded organelles is an important process for various cellular functions including membrane transport, secretion, and axonal transport. Cytoplasmic dynein, a ubiquitous minus end-directed microtubule-based motor protein, is believed to be responsible for the retrograde transport of membranous organelles from the synapse to the cell body in fast axonal transport. The cytoplasmic dynein complex is composed of two ~530 kDa heavy chains, and intermediate chains of ~74 kDa and ~53-59 kDa.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Dynein
Applications Flow Cytometry, Immunoprecipitation, Western Blot, RNA Immunoprecipitation, Immunocytochemistry
Classification Monoclonal
Clone 74.1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1mg/mL BSA and 0.05% sodium azide
Gene DYNLL2
Gene Accession No. P61285, P63167, P63168, P63170, Q3MHR3, Q78P75, Q96FJ2, Q9D0M5
Gene Alias 1700064A15Rik; 6720463E02Rik; 8 kDa dynein light chain; 8 kDa dynein light chain b; 8kD LC; 8kDa LC; 8kDLC; C87222; CDLC2; cytoplasmic dynein light polypeptide; cytoplasmic dynein light polypeptide 1; cytoplasmic light-chain dynein; cytosolic DH IC-1; DLC1; Dlc2; DLC8; DLC8b; DNCL1; DNCL1B; Dnclc1; dynein LC8; dynein light chain 1, cytoplasmic; Dynein light chain 2, cytoplasmic; dynein light chain LC8-type 1; Dynein light chain LC8-type 2; dynein light chain-2; dynein, cytoplasmic, light chain 1; dynein, cytoplasmic, light peptide; dynein, cytoplasmic, light polypeptide 1; dynein, light chain, LC8-type 1; dynein, light chain, LC8-type 2; DYNLL1; DYNLL2; HDLC1; LC8; LC8; PIN; LC8a; LOC540369 protein; mPIN; PIN; Protein inhibitor of neuronal nitric oxide synthase; protein inhibitor of nitric oxide synthase; radial spoke 22 homolog; RSPH22; similar to cytoplasmic dynein light chain 1
Gene Symbols DYNLL1, DYNLL2
Host Species Mouse
Immunogen Purified bovine brain cytoplasmic dynein.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 140734, 140735, 404151, 540369, 56455, 58945, 68097, 8655
Target Species Bovine, Human, Multi-species, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2b
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