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CDK11 Polyclonal Antibody, Bethyl Laboratories

Catalog No. p-7143980
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50-157-1368 10 μL
50-157-1367 100 μL
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Catalog No. 50-157-1368 Supplier Bethyl Laboratories, Inc Supplier No. IHC00035T
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, X. laevis, X. tropicalis, Chicken, Turkey, Bovine, Dog, Horse, Rabbit, Guinea pig_10141, Pig, Panda and Orangutan

The PITSLRE beta1 protein, a distantly related member of the Cdk family of protein kinases, induces apoptosis after low levels of ectopic expression. Apoptosis, or programmed cell death, is similarly induced by ectopic expression of an amino terminal deletion mutant retaining the catalytic and carboxyterminal domains of PITSLRE beta1, but not by other mutants lacking Histone H1 kinase activity or by other Cdk family members. The terminology for the ten isoforms of the PITSLRE subfamily of proteins is based on the conserved PSTAIRE box region of Cdc2 p34. Depending on which of the PITSLRE genes produce the protein, the cDNA and protein are designated alpha, beta or gamma (i.e., PITSLRE A gene, alpha; PITSLRE B gene, beta and PITSLRE C gene, gamma). Some of the isoforms such as PITSLRE alpha1 (T cells) and PITSLRE beta1 (B cells and brain), are expressed in specific cell types, while others are expressed ubiquitously.

Specifications

Antigen CDK11
Applications Immunohistochemistry
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene CDK11A
Gene Accession No. Q9UQ88
Gene Alias CDC2L2, CDC2L3, CDK11, CDK11 p110, CDK11 p46, CDK11 p58, CDK11A, CDK8 like cyclin dependent kinase, Cell division cycle 2 like 2 (PITSLRE proteins), Cell division cycle 2 like protein kinase 2, Cell division cycle 2-like protein kinase 2, Cell division protein kinase 11A, Cyclin dependent kinase (CDC2 like) 11, Cyclin-dependent kinase 11A, Death preventing kinase, Galactosyltransferase associated protein kinase p58/GTA, Galactosyltransferase-associated protein kinase p58/GTA
Gene Symbols CDK11A
Host Species Rabbit
Immunogen Between 730 and C-term
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 728642
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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