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Invitrogen™ C6orf57 Polyclonal Antibody
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Catalog No. PIPA556871
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Quantity:
100 μL
Catalog No. Quantity
PIPA556871 100 μL
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Catalog No. PIPA556871

Supplier: Invitrogen™ PA556871

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SPLLCHSLRK TSSSQGGKSE LVKQSLKKPK LPEGRFDAPE DSHLEKEPLE KFPDDVNPVT KEKGGPRGPE PTRYGDWERK GRCID Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 78%.

Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol (PubMed:24954416). Binds to the flavoprotein subunit Sdha in its FAD-bound form, blocking the generation of excess reactive oxigen species (ROS) and facilitating its assembly with the iron-sulfur protein subunit Sdhb into the SDH catalytic dimer.
TRUSTED_SUSTAINABILITY

Specifications

Antigen C6orf57
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.10 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SDHAF4
Gene Accession No. Q5VUM1
Gene Alias 1110058L19Rik; 1700001E18Rik; C6orf57; hypothetical protein LOC685888; LOC685888; SDH assembly factor 4; Sdh8; SDHAF4; Succinate dehydrogenase assembly factor 4, mitochondrial; succinate dehydrogenase complex assembly factor 4; UPF0369 protein C6orf57; UPF0369 protein C6orf57 homolog
Gene Symbols SDHAF4
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human C6orf57. Recombinant protein control fragment (Product #RP-94909).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 135154
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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