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Invitrogen™ ATG14 Monoclonal Antibody (1F7C10)
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Catalog No. PIMA538448
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100 μg
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Catalog No. Quantity
PIMA538448 100 μg
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Catalog No. PIMA538448 Supplier Invitrogen™ Supplier No. MA538448
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Description

Mouse Monoclonal Antibody

This antibody has been tested in indirect ELISA.

ATG14 (Autophagy related protein homolog 14) is encoded by the ATG14 gene and is located on chromosome 14 in humans. It is also known as ATG14L or BARKOR (Beclin 1-associated autophagy-related key regulator). Autophagy is an evolutionarily conserved process that involves recycling of misfolded cellular proteins and degradation of dysfunctional organelles. Autophagy is induced as a cellular response to nutrient stress which includes the formation of autophagosomes, fusion of these with the lysosome and formation of the autophagolysosome. The Class III PI3-Kinase, Vps34 and its interacting partner Beclin 1 have been shown to form a complex which specifically includes ATG 14 (type 1) or UVRAG (type 2). Atg 14 guides the type 1 complex to the preautophagosomal structure (PAS) and is critical for the initiation of autophagosome formation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ATG14
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 1F7C10
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene Atg14
Gene Accession No. Q6ZNE5
Gene Alias 4832427M01; Atg14; ATG14 autophagy related 14 homolog; Atg14L; Atg14-like protein; autophagy related 14; autophagy-related protein 14-like protein; Bakor; Barkor; beclin 1-associated autophagy-related key regulator; Beclin 1-Interacting protein; D14Ertd114e; D14Ertd436e; Kiaa0831; RGD1304610; VATG14 autophagy related 14 homolog
Gene Symbols Atg14
Host Species Mouse
Immunogen Purified recombinant fragment of human ATG14L (aa: 43-303) expressed in E. Coli.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22863
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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