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Description
CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation. [provided by RefSeq
Specifications
Specifications
| Antigen | K(lysine) acetyltransferase 2B |
| Applications | ELISA, KnockDown, Western Blot |
| Classification | Monoclonal |
| Clone | 1H2 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a partial recombinant PCAF. |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | KAT2B |
| Gene Accession No. | BC060823 |
| Gene Alias | CAF/P/P/CAF/PCAF |
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