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STEMCELL Technologies Anti-Mouse CD117 Antibody, Clone ACK2, Size: 50 µg
Supplier: STEMCELL Technologies 60034.1
Clone ACK2 is a rat monoclonal antibody that reacts with mouse CD117 (c-Kit), an ~145 kDa type 1 transmembrane receptor for c-Kit ligand (stem cell factor/steel factor) that is broadly expressed on hematopoietic stem cells in bone marrow, including pluripotent and erythroid progenitor cells and B and T lymphocyte precursors, as well as on mast cells. Verified for use with flow cytometry assays, use this antibody in applications requiring the detection of CD117 (c-Kit). Mutations in CD117 are associated with various types of tumors and the piebald trait, an autosomal dominant abnormality of pigmentation. It has been reported that binding of the ACK2 antibody blocks the function of CD117. Visit STEMCELL.com for more information and related products.
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