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Fetal Hemoglobin Mouse anti-Human, PE, Clone: 2D12, BD

Catalog No. BDB560041 Shop All BD Biosciences Products
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BDB560041 0.1 mg
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Catalog No. BDB560041 Supplier BD Biosciences Supplier No. 560041
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Description

Mouse Monoclonal Antibody

Reacts with fetal hemoglobin (HbF), a form of hemoglobin present during fetal development. HbF resembles adult hemoglobin (HbA) in possessing two alpha chains but differs in possessing two gamma instead of two beta chains. In normal adults, synthesis of HbF does persist at very low levels (<1% of total Hb) and is restricted to a small population of erythrocytes called F cells. Hemoglobin F-expressing erythrocytes are normally seen during pregnancy. An increase in the expression of fetal hemoglobin in adult peripheral red blood cells is a common feature in the genetic disorders of hemoglobin, sickle-cell disease (SCD) and beta thalassemia.

TRUSTED_SUSTAINABILITY

Specifications

Antigen Fetal Hemoglobin
Applications Flow Cytometry
Classification Monoclonal
Clone 2D12
Concentration 0.2mg/mL
Conjugate PE
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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